Anti-Mullerian Hormone Test to Determine Fertility. AMH and Infertility.



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AMH Test to Determine Fertility

What is AMH ?

AMH stands for Anti-Mullerian Hormone. Since AMH is produced directly by the ovarian follicles, AMH levels correlate with the number of antral follicles in the ovaries . It has been documented that women with lower AMH  have lower antral follicular counts and produce a lower number of oocytes compared with women with higher levels.

 AMH Reference ranges

 Ovarian Fertility Potential            pmol/L 

Optimal Fertility                             28.6 pmol/L - 48.5 pmol/L

Satisfactory Fertility                      15.7 pmol/L - 28.6 pmol/L

Low Fertility                                   2.2 pmol/L - 15.7 pmol/L

 AMH levels do not vary with the menstrual cycle and  can be measured independently of the day of the menstrual cycle.

AMH can be used for

 1.       Evaluating Fertility Potential and ovarian response in IVF – Serum AMH levels correlate with the number of early antral follicles. This makes is useful for prediciting your ovarian response in an IVF cycle. Women with low AMH levels are more likely to be poor ovarian responders.

2.       Measuring Ovarian Aging – Diminished ovarian reserve, is signaled by reduced baseline serum AMH concentrations. Women with poor ovarian reserve who have entered the oopause have low levels of AMH.

The other tests to check ovarian reserve include checking your inhibin levels.

However, these are new and expensive tests, and is still not easily available. This is why the gold standard for ovarian reserve testing is still the Day 3 FSH level.

 

 

 
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  Dr Malpani, Malpani Infertility Clinic.
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