| Malpani Infertility Clinic is very pleased to be able to provide the facility of PGD - preimplantation genetic diagnosis - the newest ART for the first time in India. We are one of the few clinics which offers this service in India, and have achieved India's first pregnancy after PGD. PGD, or preimplantation genetic diagnosis, is a new technique, which marries the recent spectacular advances in molecular genetics and assisted reproductive technology (ART).
Preimplantation genetic diagnosis enables physicians to identify genetic diseases in the embryo, prior to implantation, before the pregnancy is established.
PGD was developed for patients who were at risk of having children with serious genetic disorders, such as hemophilia, which often discouraged them having their own biological children. These couples are often faced with attempting a type of "Russian Roulette" to have children, many times having to confront the difficult decision to terminate an affected pregnancy.
Consider a woman known to be carrying the gene for hemophilia. She has a 50% risk of an affected male in each pregnancy. While her daughters have a 50% risk of being carriers, they are going to be clinically normal. She may not wish to become pregnant if she has to make decisions about an affected child in a viable pregnancy.
However, she would become pregnant if she knew she had conceived a daughter -- and with preimplantation diagnosis this possibility becomes a reality.
PGD thus eliminates the need for possible pregnancy termination after prenatal diagnosis of a fetus with hemophilia. How is PGD performed? What are the risks?
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