If you have only two embryos, should you transfer both of them ? or should you transfer one and freeze the other one?

This is a common quandary for patients with a poor ovarian response !

If you have 2 top-quality blastocysts, what should your strategy be ? Should you transfer one and freeze the other ? Or transfer both together?

If you put both together, you increase your chance of getting pregnant in that cycle - but this is an unfair comparison - after all, you shouldn't compare apples to oranges !

You should compare transferring two embryos at one time , with transferring one embryo at a time in two consecutive cycles.

And the pregnancy rate with transferring a single embryo in two consecutive cycles - a sequential single embryo transfer ( SET) is actually better , because you need to add the chances of getting pregnant in two cycles.

The cumulative conception rate with two SETs is better that transferring two embryos in a single cycle.

The risk for the babies is also less, because you don't have to worry about the problem of preterm births because of a twin pregnancy

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Source : https://blog.drmalpani.com/2020/02/if-you-have-only-two-embryos-should-you.html
Authored by : Dr Aniruddha Malpani, MD and reviewed by Dr Anjali Malpani.

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