The purpose of an IVF superovulation protocol is to help
you grow lots of follicles, which is why we use gonadotropin injections which
contain 2 hormones - FSH and LH.
One of the problems is that the LH hormone can sometimes
play the role of a rogue.
If there is an early LH surge, the follicles can rupture
too early , and we may not be able to pick up an egg at all.
This used to be a major problem in the past, which has now
been solved by using either GnRH agonists, or GnRH antagonists, which prevent these LH
Sometimes the LH surge may not be enough to cause
premature follicular rupture, which means we can still collect eggs. However, a
minor LH surge can cause premature luteinization , and as a result of the high
progesterone levels this causes on the day of egg collection, the endometrial receptivity
may be compromised.
This is why many clinics are now freezing all the embryos,
so we do not transfer embryos in the fresh cycle at all. We can then transfer the
frozen embryos in a follow up cycle , where we can prepared the endometrium for
optimal receptivity using exogenous hormones such as estradiol.
What to find an IVF clinic which respects your time and