A patient sent me this email

I am doing an IVF cycle, and my Day 6 results are as follows: E2- 1776 (great result) PO- 0.6 nmol/l LH 1.6 mIU/mL I am wondering if LH or Progesterone can be too low and should the cycle be cancelled. I am on Puregon- 300iu Menopur- 1 vial Orgalutran- 1 syringe Thanks

I am very pleased when patients are well-informed, and take an active and intelligent interest in their treatment !

Yes, the medical jargon can be quite confusing, and doctors don't make it easier, because they rarely bother to explain what's happening.

This is why the internet can be such a valuable resource for infertile women, who want to learn as much as possible about their IVF treatment

I reassured her.

 A high E2 ( estradiol) level means your ovaries are responding well, and this is a good sign. The LH and progesterone are meant to be low during superovulation , because you are being downregulated with Orgalutron ( a GnRH antagonist). You have had a text book response, and there's no need to cancel the cycle !
Authored by : Dr Aniruddha Malpani, MD and reviewed by Dr Anjali Malpani.

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