After more than 10 years of increasing evidence that the initially promised effects of PGS/PGT-A on IVF outcomes (improved pregnancy, live birth and diminished miscarriage rates) are unachievable (Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology, 2018), PGS/PGT-A remains a costly procedure in search of a clinical application.

The time appears to have come to put an end to the clinical utilization of PGS/PGT-A outside of clinical trials, given that the procedure has not only failed to fulfill promises but has also has caused harm to many patients through disposal of large numbers of embryos with normal pregnancy potential. In addition, based on the mistaken assumption that they no longer produced euploid embryos, some women gave up on their own eggs prematurely and pursued egg donation unnecessarily.

Read more athttps://www.rbmojournal.com/article/S1472-6483(18)30330-4/fulltext
Authored by : Dr Aniruddha Malpani, MD and reviewed by Dr Anjali Malpani.

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